Trivia for The Disaster Artist
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- Tommy Wiseau and Greg Sestero gave their approval to the casting of Dave Franco as Greg Sestero.
- James Franco described the script as "a cross between Boogie Nights (1997) and The Master (2012)" (both films were written and directed by Paul Thomas Anderson).
- James Franco played James Dean in a 2001 television movie biopic. Dean was a huge influence on Tommy Wiseau, and the infamous "You're tearing me apart!" moment in The Room (2003) was inspired by Rebel Without a Cause (1955). James Franco plays Tommy Wiseau in this film.
- This is Josh Hutcherson and James Franco's third collaboration as actor and director, following In Dubious Battle (2016) and The Long Home (2017).
- Greg Sestero stated that when he was writing the book, Tommy Wiseau said that only two actors could play him in the adaptation: James Franco or Johnny Depp.
- Angelyne makes a cameo as herself.
- James Franco was mentioned in "The Disaster Artist," the book on which this film is based.
- At a Q&A screening of The Room (2003) (before production of this film began), Greg Sestero expressed interest in playing the actor who was originally cast as Mark, who Wiseau fired and replaced with Sestero himself.
- This film marks Zac Efron and Dave Franco's fourth collaboration after Charlie St. Cloud (2010), Neighbors (2014), and Neighbors 2: Sorority Rising (2016).
- Zac Efron, Zoey Deutch and Jason Mantzoukas all appeared in Dirty Grandpa (2016).
- James Franco, Zoey Deutch, Bryan Cranston, Megan Mullally and Casey Wilson all appeared in Why Him? (2016).
- Greg Sestero appears in the movie as a casting agent.
- Paul Scheer, June Diane Raphael and Jason Mantzoukas, the hosts of the "How Did This Get Made" podcast, have discussed The Room (2003) in episode 23.
- James Franco spoke like Tommy Wiseau throughout each day's filming, and even directed using Wiseau's distinctive voice and syntax, though Jason Mantzoukas said that Franco did not direct in character and only spoke like Wiseau. Seth Rogen admitted he had a hard time being directed by Franco while being interviewed on The Howard Stern Show. Rogen said during the first two days, he had a hard time containing his laughter as Franco was speaking as Tommy Wiseau with his notable European accent. Franco told Rogen he would get used to it, which he eventually did.
- In The Room (2003), Tommy Wiseau directed and starred in the film. In this movie, James Franco also directed and starred.
- James Franco stayed in character as Tommy Wiseau in between shots while directing the film.
- The film received a standing ovation after the premiere at the SXSW film festival in March 2017.
- Zac Efron, who is 5'8", played Dan Janjigian, who is 6'3" tall.
- Zoey Deutch, James Franco, Bryan Cranston and Megan Mullally all starred in Why Him? (2016).
- James Franco and Seth Rogen have worked together numerous times, such as in Freaks and Geeks (1999), Knocked Up (2007), Pineapple Express (2008), This Is the End (2013), The Sound and the Fury (2014), The Interview (2014), The Night Before (2015), Sausage Party (2016), F for Franco (2016) and Zeroville (2018).
- With James Franco having stayed in character while directing the movie, Seth Rogen admitted he had a hard time being directed by Franco while being interviewed on The Howard Stern Show. Rogen said during the first two days, he had a hard time containing his laughter as Franco was speaking as Tommy Wiseau with his notable European accent. Franco told Rogen he'd get used to it, which he eventually did.
- Besides an interview for Esquire and a video for Funnyordie.com, brothers James and Dave Franco have never worked together or appeared on-screen together until this film.
- Marks the third collaboration between Seth Rogan, Zac Efron and Dave Franco who all appeared in Bad Neighbors (2014) and Bad Neighbors 2: Sorority Rising (2016)
- Tommy Wiseau appears in the movie himself. However, he plays another character (Henry).